A Iu Romanovich, Chizhov Os, Sviridov Af
Abstract
The synthesis of methyl 4,6-dideoxy-2,3-O-isopropylidene-4-C-methyl-alpha-L-mannopyranoside, a key intermediate on the preparation of C33-C38 fragment of amphotericin B, from L-rhamnose is described.
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The synthesis of methyl 4,6-dideoxy-2,3-O-isopropylidene-4-C-methyl-alpha-L-mannopyranoside, a key intermediate on the preparation of C33-C38 fragment of amphotericin B, from L-rhamnose is described.
Key concepts: Polyene, Chemistry, Macrolide Antibiotics, Stereochemistry, Antibiotics, Alpha (finance), Organic chemistry, Erythromycin