[Congenital toxoplasmosis--in prospective studies].

In the action of prevention of congenital toxoplasmosis prospective studies were carried out of women at reproductive age for detection of antibodies to Toxoplasma gondii. Women seronegative before pregnancy were subjected during pregnancy to three tests for the presence of these antibodies in the 1st, 2nd and 3rd trimester. After development of seroconversion in pregnancy further observation was conducted which made possible the diagnosis of active primary infection in pregnancy in 12 cases. Prophylactic treatment of the mothers was administered and the newborns were observed for the consequences of intrauterine infection.