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ChemInform Abstract: Synthesis and Choline Esterase Inhibiting Activity of O,O‐Diethyl‐S‐alkynyl Thiophosphates Containing Hydrophobic or Onium Groups in the Alkylthio Radical.

N. N. Godovikov, L. A. Vikhreva, E. K. Balashova, A. P. Brestkin, S. N. Moralev, V. I. Rozengart, O. E. Sherstobitov, M. I. Kabachnik

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Abstract

Abstract The bromobutyne (I) reacts with ethylmercaptide (II) to give the alkynylthioether (III) which is brominated at the triple bond by the Grignard reagent (IV), producing the ω‐bromo compound (V).

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What this paper is about

Abstract The bromobutyne (I) reacts with ethylmercaptide (II) to give the alkynylthioether (III) which is brominated at the triple bond by the Grignard reagent (IV), producing the ω‐bromo compound (V).

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Available abstract

Abstract The bromobutyne (I) reacts with ethylmercaptide (II) to give the alkynylthioether (III) which is brominated at the triple bond by the Grignard reagent (IV), producing the ω‐bromo compound (V).

Key concepts: Chemistry, Onium, Choline, Esterase, Medicinal chemistry, Organic chemistry, Polymer chemistry, Enzyme

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ChemInform Abstract: Synthesis and Choline Esterase Inhibiting Activity of O,O‐Diethyl‐S‐alkynyl Thiophosphates Containing Hydrophobic or Onium Groups in the Alkylthio Radical. — Research Paper | ScholarLens