[Immunogenicity of a conjugate of bovine serum albumin with polyacrylic acid].
Т. В. Абраменко, I.V. Vinogradov, V.A. Kabanov, Mamed Mustafaev, Rem V. Petrov
Abstract
Т. В. Абраменко, I.V. Vinogradov, V.A. Kabanov, Mamed Mustafaev, Rem V. Petrov
Abstract
The conjugate of bovine serum albumin (BSA) with polyacrylic acid, in contrast to pure BSA and the mixture of BSA with polymer, induces a pronounced primary humoral response. The injection of the conjugate in Freund's complete adjuvant leads to considerable immune response to BSA, 30-40 and 100-130 times more intensive than that produced, respectively, by the injection of the conjugate alone or BSA in the adjuvant.
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The conjugate of bovine serum albumin (BSA) with polyacrylic acid, in contrast to pure BSA and the mixture of BSA with polymer, induces a pronounced primary humoral response. The injection of the conjugate in Freund's complete adjuvant leads to considerable immune response to BSA, 30-40 and 100-130 times more intensive than that produced, respectively, by the injection of the conjugate alone or BSA in the adjuvant.
Key concepts: Conjugate, Bovine serum albumin, Immunogenicity, Adjuvant, Chemistry, Serum albumin, Polyacrylic acid, Chromatography