2002•PubMedRequires access

Synthesis and antimicrobial activity of some imidazo-[1,2-a]pyridine-2- carboxylic acid arylidenehydrazide derivatives.

Gülhan Turan‐Zitouni, Yves Blache, Kıymet Güven

Abstract

Imidazo[1,2-a]pyridine-2-carboxylic acid, ethyl esters were reacted with hydrazine hydrate to furnish imidazo[1,2-a]pyridine-2-carboxylic acid hydrazide. The hydrazides formed were treated with various aldehydes to obtain 28 imidazo[1,2-a]pyridine-2-carboxylic acid arylidenehydrazides. Antimicrobial activity of the compounds were examined.

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Key concepts: Pyridine, Hydrazide, Chemistry, Carboxylic acid, Antimicrobial, Hydrate, Hydrazine (antidepressant), Organic chemistry