1989•Journal of the Society of Cosmetic Scientists of KoreaRequires access
A Study on the Inclusion Complexation of Octyldimethyl p-aminobengoate with \brta -Cyclodextrin$
Chang-Hak Lee, Bu-Yeong So, Yeong-Su Kim
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Abstract
Inclusion complex formation of octyldimethl p-aminobenzoate with -cyclodextrin in aqueous solution and in the solid state was studied by the solubility method, spectroscopic(UV, FT-lR) and X -ray diffractometry. The solid complex of octyldimethy p-aminobenzoate with -cyclodextrin was obtained in molar ratio of 1 : 2(guest/host). A spatial relationship between host and guest molecule was clearly reflected in the magnitude of the apparent stability constant (K') and in the stoichiometry of the inclusion complex. Furthermore, a typical type Bs phase-solubility diagram was obtained for octyldimethyl p-aminobenzoate and p -cyclodextrin in water at . The results indicated that the solubility of the guest molecule was higher by the formation of -cyclodextrin inclusion complex