2013•PubMedRequires access

[Neuromyelitis optica is a frequently seen inflammatory demyelinating disease].

Nasrin Asgari, Hanne Pernille Bro Skejø, Søren Thue Lillevang, Egon Stenager

Abstract

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system with autoimmune characteristics. Serum immunoglobulin G autoantibodies have been identified in the majority of NMO patients with the water channel aquaporin-4 (AQP4) as their main target autoantigen. Clinical criteria have defined NMO and NMO-spectrum disease. The clinical features include inflammation of the optic nerve.

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Key concepts: Neuromyelitis optica, Demyelinating disease, Medicine, Autoantibody, Aquaporin 4, Multiple sclerosis, Disease, Optic neuritis