ChemInform Abstract: Reaction of Fluoroalkyl‐2‐keto Acids and Their Esters with Acetone.
В. И. Салоутин, I. A. Piterskikh, K. I. Pashkevich
Abstract
В. И. Салоутин, I. A. Piterskikh, K. I. Pashkevich
Abstract
Abstract The reaction between the polyfluoroalkylketo esters (I) and acetone (II) proceeds under mild conditions and regioselectively at the 2‐keto function to afford the methyl 2‐hydroxy‐2‐fluoroalkyl‐4‐oxovalerates (III).
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Abstract The reaction between the polyfluoroalkylketo esters (I) and acetone (II) proceeds under mild conditions and regioselectively at the 2‐keto function to afford the methyl 2‐hydroxy‐2‐fluoroalkyl‐4‐oxovalerates (III).
Key concepts: Chemistry, Acetone, Organic chemistry, Medicinal chemistry