Light chain types in plasma cells that produce IgD.
B Pernis, M Governa, D. S. Rowe
Abstract
B Pernis, M Governa, D. S. Rowe
Abstract
The IgD-immunoglobulin producing plasma cells of six human spleens have been localized with specific antisera and the type of the light chains present in each of them has been determined by sequential staining with anti-K and anti-L antisera. About 87 per cent of IgD cells have L-type light chains. This is in accord with the prevalence of L-type light chains in IgD myeloma proteins.
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The IgD-immunoglobulin producing plasma cells of six human spleens have been localized with specific antisera and the type of the light chains present in each of them has been determined by sequential staining with anti-K and anti-L antisera. About 87 per cent of IgD cells have L-type light chains. This is in accord with the prevalence of L-type light chains in IgD myeloma proteins.
Key concepts: Immunoglobulin D, Immunoglobulin light chain, Antiserum, Antibody, Molecular biology, Myeloma protein, Biology, Chemistry