Noninvasive Prenatal Diagnosis Using Fetal Cells in Maternal Blood
Yuk Ming Dennis Lo
Abstract
Yuk Ming Dennis Lo
Abstract
It has been a long-sought goal of human genetics to develop safe and reliable prenatal diagnostic procedures that constitute no risk to the fetus. At present, the safety of available methods is limited by the need to obtam fetal tissues through invasive means, such as chorlomc villus sampling (CVS) and amniocentesis, which constitute a risk to the fetus. One potential noninvasive approach for prenatal diagnosis is to use fetal cells that have entered into maternal circulation during pregnancy as a source of fetal material for analysis. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
It has been a long-sought goal of human genetics to develop safe and reliable prenatal diagnostic procedures that constitute no risk to the fetus. At present, the safety of available methods is limited by the need to obtam fetal tissues through invasive means, such as chorlomc villus sampling (CVS) and amniocentesis, which constitute a risk to the fetus. One potential noninvasive approach for prenatal diagnosis is to use fetal cells that have entered into maternal circulation during pregnancy as a source of fetal material for analysis. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Key concepts: Amniocentesis, Fetus, Prenatal diagnosis, Obstetrics, Medicine, Pregnancy, Chorionic villus sampling, Fetal circulation