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Antihepatotoxic Activity of Cassia tora Leaf Extract

Tapan Kumar Maity, Subhash Chandra Mandal, Mahadeb Pal, Basudeb Saha

Abstract

Methanolic extract of Cassia tora leaves was evaluated for its hepatoprotective activity in rats by inducing hepatotoxicity with paracetamol (acute model). The extract at a dose of 400 mg/kg orally exhibited significant protective effect by lowering the serum levels of transaminase (SGOT and SGPT), bilirubin, and alkaline phosphatase (ALP). The effects produced were comparable to that of a standard hepatoprotective agent.

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Key concepts: Cassia tora, Alkaline phosphatase, Cassia, Bilirubin, Traditional medicine, Chemistry, Aspartate transaminase, Pharmacology