ChemInform Abstract: A Convenient One‐Pot Synthesis of 3‐Thio‐Substituted Coumarins.
V. K. AHLUWALIA, Mohammad Alauddin, Chandra Has Khanduri, V. D. MEHTA
Abstract
V. K. AHLUWALIA, Mohammad Alauddin, Chandra Has Khanduri, V. D. MEHTA
Abstract
Abstract Alkylation of the heterocyclic thiols (I) with chloroacetonitrile (II) yields the cyanomethyl sulfides (III) which undergo ring closure with the o‐hydroxybenzaldehydes (IV), forming the coumarinimines (V).
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Abstract Alkylation of the heterocyclic thiols (I) with chloroacetonitrile (II) yields the cyanomethyl sulfides (III) which undergo ring closure with the o‐hydroxybenzaldehydes (IV), forming the coumarinimines (V).
Key concepts: Chemistry, Thio-, Ring (chemistry), Alkylation, Closure (psychology), Medicinal chemistry, Combinatorial chemistry, Organic chemistry