[Topical treatment of psoriasis with calcipotriol. Report of clinical experience].

BACKGROUND: Numerous clinical studies have demonstrated the efficacy of calcipotriol, a synthetic vitamin D3 analogue, in the treatment of mild to moderate chronic psoriasis. METHOD: Report on clinical experience of 40 psoriasis patients treated with calcipotriol, alone or in combination with phototherapy. RESULTS: After four weeks of treatment, the condition had largely cleared up in eleven out of 18 patients (61%) receiving calcipotriol alone, and in 20 out of 22 patients (91%) receiving combination treatment with UVB or UVA plus UVB. The new anti-psoriasis agent was well tolerated and readily accepted by the patients. CONCLUSION: Calcipotriol represents a valuable addition to the available therapy spectrum in chronic psoriasis.