[Spinal cord and cauda equina compression in 2 patients with beta-thalassemia intermedia].
M Coraddu, Francesco Floris, V. Meleddu, Giancarlo Nurchi, Enrico Cacace, R Contini, G Perpignano
Abstract
M Coraddu, Francesco Floris, V. Meleddu, Giancarlo Nurchi, Enrico Cacace, R Contini, G Perpignano
Abstract
Spinal cord compression as a consequence of mass lesions due to extramedullary hematopoiesis is a well described but rare syndrome occurring in thalassemia and some other hematologic conditions. The authors report two cases of patients with a genetic variant of beta-thalassemia, who suffered from a progressive compression of the spinal cord in one case, of the cauda equina in the other caused by epidural hematopoietic tissue. The first patient recovered after partial surgical removal of this tissue and subsequent radiotherapy. The second one recovered after only radiotherapy.
OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Spinal cord compression as a consequence of mass lesions due to extramedullary hematopoiesis is a well described but rare syndrome occurring in thalassemia and some other hematologic conditions. The authors report two cases of patients with a genetic variant of beta-thalassemia, who suffered from a progressive compression of the spinal cord in one case, of the cauda equina in the other caused by epidural hematopoietic tissue. The first patient recovered after partial surgical removal of this tissue and subsequent radiotherapy. The second one recovered after only radiotherapy.
Key concepts: Medicine, Cauda equina, Extramedullary hematopoiesis, Spinal cord compression, Thalassemia, Spinal cord, Beta thalassemia, Radiation therapy