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OSTEOSARCOMA OF THE DIAPHYSIS OF LONG BONES: CLINICOPATHOLOGIC FEATURES AND TREATMENT OF 51 CASES

Franklin H. Sim, F J Frassica, K. Krishnan Unni

Open publisher page 19 citations

Abstract

Of 1000 osteosarcoma cases recorded in the Mayo Clinic records, approximately 7% of the lesions occurred in the diaphysis of long bones, mostly in the femur, tibia, and humerus. The average age of the patients with these lesions was 28 years (range: 8 to 67). The duration of their symptoms before diagnosis was greater than that for patients with conventional osteosarcoma in the metaphysis. In approximately 20% of the cases, the radiographic appearance mimicked that of Ewing's sarcoma. Amputation surgery was the major form of treatment. The 2-, 5- and 15-year survival was 42%, 29%, and 20%, respectively.

About this research paper

What this paper is about

Of 1000 osteosarcoma cases recorded in the Mayo Clinic records, approximately 7% of the lesions occurred in the diaphysis of long bones, mostly in the femur, tibia, and humerus. The average age of the patients with these lesions was 28 years (range: 8 to 67). The duration of their symptoms before diagnosis was greater than that for patients with conventional osteosarcoma in the metaphysis. In approximately 20% of the cases, the radiographic appearance mimicked that of Ewing's sarcoma. Amputation surgery was the major form of treatment. The 2-, 5- and 15-year survival was 42%, 29%, and 20%, respectively.

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OpenAlex reports 19 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Of 1000 osteosarcoma cases recorded in the Mayo Clinic records, approximately 7% of the lesions occurred in the diaphysis of long bones, mostly in the femur, tibia, and humerus. The average age of the patients with these lesions was 28 years (range: 8 to 67). The duration of their symptoms before diagnosis was greater than that for patients with conventional osteosarcoma in the metaphysis. In approximately 20% of the cases, the radiographic appearance mimicked that of Ewing's sarcoma. Amputation surgery was the major form of treatment. The 2-, 5- and 15-year survival was 42%, 29%, and 20%, respectively.

Key concepts: Medicine, Diaphysis, Osteosarcoma, Humerus, Metaphysis, Tibia, Femur, Amputation

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OSTEOSARCOMA OF THE DIAPHYSIS OF LONG BONES: CLINICOPATHOLOGIC FEATURES AND TREATMENT OF 51 CASES — Research Paper | ScholarLens