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[Comparative studies of rhombencephalon vascularization in rabbit and man in light of anatomic and microangiographic studies].

Grażyna Michalska-Krzanowska

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Abstract

A comparative study of a microvascularization of the rhombencephalon, especially pre- and capillary system, in rabbits and in humans was performed. It was intended to find out whether there were any similarities and differences in rhombencephalon microvascularization of a rabbit and man. The study was carried out on 75 (50--female, 25--male) mixed-race rabbits aged 4 months, as well as on 30 (15--females, 10--males) human brains that had been dissected free from cadavers, aged from 20 up to 70 years. Angiography of sections of the rhombencephalon in rabbits and cadavers was performed. The vessels were investigated after the introduction of Micropaque contrast medium, under controlled pressure, into an investigated vessel. Intravital injection of the contrast into rabbit's vessel was beneficial for the experiment. Radiography of intact brains as well as sections of the frontal plane was accomplished. Large arterial vessels were measured, with the results being subjected to statistical analysis (Table 1-2, Fig. 1-7). Microvascularization of the medulla oblongata and of the pons in rabbits were similar to those in its human counterparts, whereas the vascular system of the cerebellum was different. The results of micrographic studies were not always the same as described by Bochenek et al. The anatomical forms that had not been previously described were noted: para--medial arteries to the medulla oblongata and the pons; lateral arteries to the medulla oblongata and the pons; posterior arteries to the medulla oblongata; branches of the upper artery of the cerebellum branching and the simple ones with few lateral branches. The central or medial artery that follows the central sulcus was separate.

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A comparative study of a microvascularization of the rhombencephalon, especially pre- and capillary system, in rabbits and in humans was performed. It was intended to find out whether there were any similarities and differences in rhombencephalon microvascularization of a rabbit and man. The study was carried out on 75 (50--female, 25--male) mixed-race rabbits aged 4 months, as well as on 30 (15--females, 10--males) human brains that had been dissected free from cadavers, aged from 20 up to 70 years. Angiography of sections of the rhombencephalon in rabbits and cadavers was performed. The vessels were investigated after the introduction of Micropaque contrast medium, under controlled pressure, into an investigated vessel. Intravital injection of the contrast into rabbit's vessel was beneficial for the experiment. Radiography of intact brains as well as sections of the frontal plane was accomplished. Large arterial vessels were measured, with the results being subjected to statistical analysis (Table 1-2, Fig. 1-7). Microvascularization of the medulla oblongata and of the pons in rabbits were similar to those in its human counterparts, whereas the vascular system of the cerebellum was different. The results of micrographic studies were not always the same as described by Bochenek et al. The anatomical forms that had not been previously described were noted: para--medial arteries to the medulla oblongata and the pons; lateral arteries to the medulla oblongata and the pons; posterior arteries to the medulla oblongata; branches of the upper artery of the cerebellum branching and the simple ones with few lateral branches. The central or medial artery that follows the central sulcus was separate.

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Available abstract

A comparative study of a microvascularization of the rhombencephalon, especially pre- and capillary system, in rabbits and in humans was performed. It was intended to find out whether there were any similarities and differences in rhombencephalon microvascularization of a rabbit and man. The study was carried out on 75 (50--female, 25--male) mixed-race rabbits aged 4 months, as well as on 30 (15--females, 10--males) human brains that had been dissected free from cadavers, aged from 20 up to 70 years. Angiography of sections of the rhombencephalon in rabbits and cadavers was performed. The vessels were investigated after the introduction of Micropaque contrast medium, under controlled pressure, into an investigated vessel. Intravital injection of the contrast into rabbit's vessel was beneficial for the experiment. Radiography of intact brains as well as sections of the frontal plane was accomplished. Large arterial vessels were measured, with the results being subjected to statistical analysis (Table 1-2, Fig. 1-7). Microvascularization of the medulla oblongata and of the pons in rabbits were similar to those in its human counterparts, whereas the vascular system of the cerebellum was different. The results of micrographic studies were not always the same as described by Bochenek et al. The anatomical forms that had not been previously described were noted: para--medial arteries to the medulla oblongata and the pons; lateral arteries to the medulla oblongata and the pons; posterior arteries to the medulla oblongata; branches of the upper artery of the cerebellum branching and the simple ones with few lateral branches. The central or medial artery that follows the central sulcus was separate.

Key concepts: Medulla oblongata, Anatomy, Pons, Cerebellum, Medulla, Medicine, Posterior inferior cerebellar artery, Central nervous system

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[Comparative studies of rhombencephalon vascularization in rabbit and man in light of anatomic and microangiographic studies]. — Research Paper | ScholarLens