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[Risk factors for gestational trophoblastic tumors following complete hydatidiform mole].

Wojciech Grzybowski, A Płoszyński, Jerzy Mielnik, M Adamcio-Deptulska, Krzysztof Preis, Danuta Wojciechowska

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Abstract

OBJECTIVES: The aim of our study was to determine the factors associated with higher incidence of trophoblastic tumours following complete hydatidiform mole. MATERIAL AND METHODS: Epidemiological and clinical factors were studied in eighty five patients with complete hydatidiform mole evacuated from 1973 to 1997 in Department of Obstetrics and Gynecology Medical University of Gdańsk. Univariate and multivariate analysis were used to study of group. RESULTS AND CONCLUSIONS: In the analysis of 85 patients we found three prognostically independent factors that were associated with higher incidence of trophoblastic tumours after the complete hydatidiform mole: pre-evacuation hCG level, presence of prominent theca lutein cysts (greater than 6 cm in diameter) and molar pregnancy in the patient's past history. Persistent vomiting was a symptom of lower significance as a risk factor of trophoblastic tumour.

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OBJECTIVES: The aim of our study was to determine the factors associated with higher incidence of trophoblastic tumours following complete hydatidiform mole. MATERIAL AND METHODS: Epidemiological and clinical factors were studied in eighty five patients with complete hydatidiform mole evacuated from 1973 to 1997 in Department of Obstetrics and Gynecology Medical University of Gdańsk. Univariate and multivariate analysis were used to study of group. RESULTS AND CONCLUSIONS: In the analysis of 85 patients we found three prognostically independent factors that were associated with higher incidence of trophoblastic tumours after the complete hydatidiform mole: pre-evacuation hCG level, presence of prominent theca lutein cysts (greater than 6 cm in diameter) and molar pregnancy in the patient's past history. Persistent vomiting was a symptom of lower significance as a risk factor of trophoblastic tumour.

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Available abstract

OBJECTIVES: The aim of our study was to determine the factors associated with higher incidence of trophoblastic tumours following complete hydatidiform mole. MATERIAL AND METHODS: Epidemiological and clinical factors were studied in eighty five patients with complete hydatidiform mole evacuated from 1973 to 1997 in Department of Obstetrics and Gynecology Medical University of Gdańsk. Univariate and multivariate analysis were used to study of group. RESULTS AND CONCLUSIONS: In the analysis of 85 patients we found three prognostically independent factors that were associated with higher incidence of trophoblastic tumours after the complete hydatidiform mole: pre-evacuation hCG level, presence of prominent theca lutein cysts (greater than 6 cm in diameter) and molar pregnancy in the patient's past history. Persistent vomiting was a symptom of lower significance as a risk factor of trophoblastic tumour.

Key concepts: Medicine, Trophoblastic neoplasm, Molar pregnancy, Incidence (geometry), Gynecology, Obstetrics, Trophoblastic Tumor, Univariate analysis

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[Risk factors for gestational trophoblastic tumors following complete hydatidiform mole]. — Research Paper | ScholarLens