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Identification of pyrrolizidine alkaloids (Senecio longilobus).

Segall Hj, Molyneux Rj

Abstract

Pyrrolizidine alkaloids derived from Senecio longilobus have been rapidly isolated and identified. The potential of isolating individual pyrrolizidine alkaloids utilizing high pressure liquid chromatography is discussed. The utilization of a single 10 mu CN column to isolate closely related pyrrolizidine alkaloids suggests a marked improvement in pyrrolizidine alkaloid chemistry.

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Key concepts: Pyrrolizidine, Senecio, Pyrrolizidine alkaloid, Alkaloid, Botany, Biology, Chemistry