[Determination of acute-inflammatory-phase proteins in the blood serum of volunteers consuming diets with various protein levels consisting of optimum protein constituents].

The immunodiffusion technique was employed to study the blood serum content of acute inflammation phase reactants (transferrin, alpha 1-antitrypsin, ceruloplasmin, alpha 2-macroglobulin, fibrinogen, plasminogen, orosomucoid, haptoglobin, albumin and prealbumin) in 8 practically healthy men in the background of insufficient protein supply to the body. It was established that reduction of protein quota in the diet to 5.0-8.2 g/day (according to nitrogen) led to a decrease in the concentration of transferrin, ceruloplasmin, alpha 1-antitrypsin, albumin and prealbumin. It is concluded that reduction in the titers of the study proteins under protein deficiency may bring about the loss or weakening of the important components of the body defense, which are mediated by the above-mentioned protein structures.