1982•PubMedRequires access
Thymoxamine versus pilocarpine in the reversal of phenylephrine-induced mydriasis.
Saheb Ne, D. Lorenzetti, D S East, S Salpeter-Carlton
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Abstract
Thymoxamine, a selective alpha-adrenergic blocker, was compared with pilocarpine in 19 patients for its reversal of phenylephrine-induced mydriasis. Both agents constricted the pupil to its original size in less than half an hour, and thymoxamine's half-life was twice that of pilocarpine's. The advantages of thymoxamine miosis, particularly in patients with narrow angles, are discussed.