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[Assessment of the brainstem and the cerebellar lesions and myelination using magnetic resonance images in children with Down syndrome].

Hirofumi Komaki, Hirotoshi Hamaguchi, Tadafumi Hashimoto

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Abstract

Magnetic resonance images were carried out in the children with Down syndrome aged 2-4 years old compared with the values of the age-matched controls. The pons and cerebellar vermis were significantly smaller and the cerebral peduncles were narrower in Down syndrome. None of the patients showed delay of myelination. These findings suggest hypoplasia of the pons and cerebellum in Down syndrome.

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What this paper is about

Magnetic resonance images were carried out in the children with Down syndrome aged 2-4 years old compared with the values of the age-matched controls. The pons and cerebellar vermis were significantly smaller and the cerebral peduncles were narrower in Down syndrome. None of the patients showed delay of myelination. These findings suggest hypoplasia of the pons and cerebellum in Down syndrome.

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OpenAlex reports 4 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Magnetic resonance images were carried out in the children with Down syndrome aged 2-4 years old compared with the values of the age-matched controls. The pons and cerebellar vermis were significantly smaller and the cerebral peduncles were narrower in Down syndrome. None of the patients showed delay of myelination. These findings suggest hypoplasia of the pons and cerebellum in Down syndrome.

Key concepts: Pons, Magnetic resonance imaging, Cerebellum, Brainstem, Hypoplasia, Cerebellar vermis, Down syndrome, Cerebellar hypoplasia (non-human)

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[Assessment of the brainstem and the cerebellar lesions and myelination using magnetic resonance images in children with Down syndrome]. — Research Paper | ScholarLens