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1989•Journal of ChemotherapyRequires access

In- VitroSusceptibility of Clinical Isolates ofPseudomonas aeruginosato β-Lactam and Aminoglycoside Antibiotics

D. Sofianou, S. Vrenas, J. Doumboyas

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Abstract

The in-vitro susceptibilities of 198 isolates of Pseudomonas aeruginosa from clinical human specimens were determined by an agar dilution technique against beta-lactams and aminoglycosides. These isolates were susceptible to imipenem, aztreonam and ceftazidime with the minimum inhibitory concentration (MIC) for 90% of the strains tested being 8, 16 and 8 micrograms/ml, respectively. Aminoglycosides, except amikacin, had low activity (MIC90 greater than 128 micrograms/ml).

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What this paper is about

The in-vitro susceptibilities of 198 isolates of Pseudomonas aeruginosa from clinical human specimens were determined by an agar dilution technique against beta-lactams and aminoglycosides. These isolates were susceptible to imipenem, aztreonam and ceftazidime with the minimum inhibitory concentration (MIC) for 90% of the strains tested being 8, 16 and 8 micrograms/ml, respectively. Aminoglycosides, except amikacin, had low activity (MIC90 greater than 128 micrograms/ml).

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Available abstract

The in-vitro susceptibilities of 198 isolates of Pseudomonas aeruginosa from clinical human specimens were determined by an agar dilution technique against beta-lactams and aminoglycosides. These isolates were susceptible to imipenem, aztreonam and ceftazidime with the minimum inhibitory concentration (MIC) for 90% of the strains tested being 8, 16 and 8 micrograms/ml, respectively. Aminoglycosides, except amikacin, had low activity (MIC90 greater than 128 micrograms/ml).

Key concepts: Aztreonam, Ceftazidime, Amikacin, Microbiology, Aminoglycoside, Imipenem, Agar dilution, Pseudomonas aeruginosa

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In- VitroSusceptibility of Clinical Isolates ofPseudomonas aeruginosato β-Lactam and Aminoglycoside Antibiotics — Research Paper | ScholarLens