[Study on DNA expression profiles in renal biopsies of patients with IgA nephropathy].
Feng Li, Ying-hao Yu, Jingsheng Xu, Fenghua Lan, Yongze Zhuang, Zhiyong Zheng, Huasheng Xiao
Abstract
Feng Li, Ying-hao Yu, Jingsheng Xu, Fenghua Lan, Yongze Zhuang, Zhiyong Zheng, Huasheng Xiao
Abstract
已有学者发现在IgA肾病的发生发展中,遗传因素发挥着重要作用[1].基因芯片技术已被广泛应用于多种疾病相关基因的筛选[2].为全面了解IgA肾病相关基因的表达情况,我们应用基因芯片检测IgA肾病和正常肾组织基因的差异表达,寻找差异表达基因与IgA肾病之间可能的内在联系.为进一步探讨IgA肾病的发病机制及临床诊断提供理论依据。
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已有学者发现在IgA肾病的发生发展中,遗传因素发挥着重要作用[1].基因芯片技术已被广泛应用于多种疾病相关基因的筛选[2].为全面了解IgA肾病相关基因的表达情况,我们应用基因芯片检测IgA肾病和正常肾组织基因的差异表达,寻找差异表达基因与IgA肾病之间可能的内在联系.为进一步探讨IgA肾病的发病机制及临床诊断提供理论依据。
Key concepts: Nephropathy, Renal biopsy, DNA, Medicine, Urology, Internal medicine, Cancer research, Chemistry