2002•PubMedRequires access
[Effects of invigorating the kidney and strengthening the bones capsule on osteoporosis in ovariectomized rats].
Shenggang Li, Xiaofeng Yang, YU De-zhi, Aimin Zhu
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Abstract
OBJECTIVE: To study the therapeutic effects of inrigorating the kidney and strengthening the bones capsule(IKSBC) on osteoporotic ovariectomized(OVX) rat model. METHODS: The concentrations of calcium, phosphorus and ALP in serum of ovariectomized rats were determined by clinical biochemical assay, and the right hind leg thighbones of ovariectomized rats were reserved for the preparation of bone specimens and were studied by bone histomorphometry. RESULTS: After treatment with IKSBC, the concentrations of calcium and phosphorus in ovariectomized rat serum were increased, the activity of ALP was decreased and the percentage of relative trabecular volume was increased significantly as compared with that before treatment(P < 0.05). CONCLUSION: IKSBC possesses some therapeutic effects on osteoporotic rat model.