2011•PubMedRequires access

[Hepatoprotective effect of thiophane in rats with experimental carbon tetrachloride-induced hepatitis].

V I Smol'iakova, Марк Борисович Плотников, Г. А. Чернышева, Илья Сергеевич Иванов, Alexandr Evgenievich Prosenko, Н. В. Кандалинцева

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Abstract

A hepatoprotective effect of thiophan was studied on the model of carbon tetrachloride-induced hepatitis in rats. Therapeutic administration of thiophan repairs the antitoxic function of liver, normalizes cytolysis marker activity, and improves the synthetic function of liver and the carbohydrate and lipid metabolism. The hepatoprotective activity of thiophan is similar to effect of silimarin.

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Available abstract

Key concepts: Carbon tetrachloride, Chemistry, Hepatitis, Liver function, Pharmacology, CCL4, Therapeutic effect, Carbohydrate