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[Stimulation of gastric acid secretion by sham feeding in patients with duodenal ulcer before and after selective proximal vagotomy].

Hans Sperup Brünner, von Ghember-Chalubinska K, Werner Scheithauer, R Schiessel

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Abstract

Gastric acid secretion stimulated by sham feeding was measured in 12 patients with duodenal ulcer before and after highly selective vagotomy and compared with the results obtained from 7 healthy controls. In the ulcer patients sham feeding resulted in a higher stimulated secretion compared to normals. In addition after sham feeding the secretion fell slower to basal levels than in the control group. Highly selective vagotomy normalized these abnormalities. We conclude, that sham feeding might be a test applicable to patients after vagotomy to predict adequate reduction of acid secretion.

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What this paper is about

Gastric acid secretion stimulated by sham feeding was measured in 12 patients with duodenal ulcer before and after highly selective vagotomy and compared with the results obtained from 7 healthy controls. In the ulcer patients sham feeding resulted in a higher stimulated secretion compared to normals. In addition after sham feeding the secretion fell slower to basal levels than in the control group. Highly selective vagotomy normalized these abnormalities. We conclude, that sham feeding might be a test applicable to patients after vagotomy to predict adequate reduction of acid secretion.

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Available abstract

Gastric acid secretion stimulated by sham feeding was measured in 12 patients with duodenal ulcer before and after highly selective vagotomy and compared with the results obtained from 7 healthy controls. In the ulcer patients sham feeding resulted in a higher stimulated secretion compared to normals. In addition after sham feeding the secretion fell slower to basal levels than in the control group. Highly selective vagotomy normalized these abnormalities. We conclude, that sham feeding might be a test applicable to patients after vagotomy to predict adequate reduction of acid secretion.

Key concepts: Vagotomy, Medicine, Sham feeding, Secretion, Internal medicine, Duodenal ulcer, Basal (medicine), Gastric acid

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[Stimulation of gastric acid secretion by sham feeding in patients with duodenal ulcer before and after selective proximal vagotomy]. — Research Paper | ScholarLens