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Cardiac angiosarcoma. Histological, immunohistochemical and ultrastructural study.

Teresa Marafioti, F Castorino, G Gula

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Abstract

A case of cardiac angiosarcoma of the right atrium in a man aged of 41 years is described. The immunohistochemical methods showed a positivity for Factor VIII, Vimentin, Lectin UEA1 and very poor reactivity for a histiocytary markers. Electron microscopy confirmed the endothelial differentiation of some tumour cells. The relations between genuine cardiac angiosarcomas, malignant fibrous histiocytomas, and Kaposi's sarcomas arising in the heart are discussed.

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What this paper is about

A case of cardiac angiosarcoma of the right atrium in a man aged of 41 years is described. The immunohistochemical methods showed a positivity for Factor VIII, Vimentin, Lectin UEA1 and very poor reactivity for a histiocytary markers. Electron microscopy confirmed the endothelial differentiation of some tumour cells. The relations between genuine cardiac angiosarcomas, malignant fibrous histiocytomas, and Kaposi's sarcomas arising in the heart are discussed.

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OpenAlex reports 7 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A case of cardiac angiosarcoma of the right atrium in a man aged of 41 years is described. The immunohistochemical methods showed a positivity for Factor VIII, Vimentin, Lectin UEA1 and very poor reactivity for a histiocytary markers. Electron microscopy confirmed the endothelial differentiation of some tumour cells. The relations between genuine cardiac angiosarcomas, malignant fibrous histiocytomas, and Kaposi's sarcomas arising in the heart are discussed.

Key concepts: Angiosarcoma, Vimentin, Immunohistochemistry, Pathology, Sarcoma, Ultrastructure, Medicine

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