ChemInform Abstract: Transition Metal Promoted Intramolecular Cyclizations of α,α‐Dichloro Esters and Acids.
Thomas K. Hayes, A. J. FREYER, Masood Parvez, Steven M. Weinreb
Abstract
Thomas K. Hayes, A. J. FREYER, Masood Parvez, Steven M. Weinreb
Abstract
Abstract Cyclization of the unsaturated α,α‐dichloro acids or esters (I) in the presence of the catalysts (II) yields the monocyclic carboxylic acid derivatives (III) and/or the bicyclic γ‐lactones (IV).
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Abstract Cyclization of the unsaturated α,α‐dichloro acids or esters (I) in the presence of the catalysts (II) yields the monocyclic carboxylic acid derivatives (III) and/or the bicyclic γ‐lactones (IV).
Key concepts: Intramolecular force, Bicyclic molecule, Catalysis, Chemistry, Transition metal, Metal, Medicinal chemistry, Organic chemistry