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[Plasma LH response to LHRH in hypothyroid and thyroxin-treated rats (author's transl)].

M Boutrand, M. Pugeat, M Fèvre, J Tourniaire

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Abstract

Plasma LH response after intravenous injection of synthetic LHRH (50 ng) was studied in male rats (normal, after thyroidectomy, after treatment by dl thyroxin 50 microgram/a day, 10 days). LH response was significantly elevated in hypothyroid animals although it was not influenced by thyroxin injections. Prolonged plasma LH half-life in hypothyroid rats can account in this result.

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What this paper is about

Plasma LH response after intravenous injection of synthetic LHRH (50 ng) was studied in male rats (normal, after thyroidectomy, after treatment by dl thyroxin 50 microgram/a day, 10 days). LH response was significantly elevated in hypothyroid animals although it was not influenced by thyroxin injections. Prolonged plasma LH half-life in hypothyroid rats can account in this result.

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Available abstract

Plasma LH response after intravenous injection of synthetic LHRH (50 ng) was studied in male rats (normal, after thyroidectomy, after treatment by dl thyroxin 50 microgram/a day, 10 days). LH response was significantly elevated in hypothyroid animals although it was not influenced by thyroxin injections. Prolonged plasma LH half-life in hypothyroid rats can account in this result.

Key concepts: Internal medicine, Endocrinology, Microgram, Thyroidectomy, Medicine, Plasma levels, Thyroid, Chemistry

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[Plasma LH response to LHRH in hypothyroid and thyroxin-treated rats (author's transl)]. — Research Paper | ScholarLens