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[Influence of Solcotrichovac vaccine on formation of neutrophil extracellular traps].

I I Dolgushin, Iu S Andreeva, A I Ryzhkova, A Iu Savochkina, Mezentseva Ea, Nikushkina Kv, О. С. Абрамовских, S I Marachev, Matveeva Dn

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Abstract

AIM: To study the influence of Solcotichovac vaccine on formation of neutrophil extracellular traps. MATERIALS AND METHODS: Solcotrichovac vaccine administered in various doses was used in order to assess the formation of neutrophil extracellular traps in peripheral blood of women of childbearing age. RESULTS: Therapeutic dose of Solcotrichovac stimulated the most prominent formation of neutrophil extracellular traps. CONCLUSION: Solcotrichovac vaccine stimulated non-specific arm of mucosal immunity due to formation of neutrophil extracellular traps and it is probable that this mechanism explains the effect of this vaccine.

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Key concepts: Neutrophil extracellular traps, Extracellular, Immunity, Immunology, Chemistry, Microbiology, Biology, Cell biology