2014•Journal watchRequires access
Hypertonic Saline for Bronchiolitis: Differing Results from Two Trials
Katherine Bakes
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Abstract
Previous studies demonstrated mixed results about the effect of hypertonic saline for the emergency department treatment of young children with bronchiolitis. Two new randomized, controlled trials add to the fray.
In one, Wu et al. enrolled 408 children <24 months of age presenting to two pediatric emergency departments with viral bronchiolitis during three bronchiolitis seasons. Patients received nebulized albuterol followed by 4 mL of nebulized 3% hypertonic saline or 0.9% normal saline, …