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[Secretion of small intestinal enzymes after section of the pancreatic duct].

Pulatov As, Glushko Lf

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Abstract

In chronic experiments on dogs, soon after ligation of the pancreatic duct, amylase increases in the peripheral blood as well as the total amylase and lipase release in liquid and solid portions of the secret from isolated parts of the small intestine. The alpha--amylase release was shown to depend on the level of the blood amylolytic activity and on secretory activity of small intestine. The alpha--amylase and lipase release is more increased at mechanical rather than at chemical stimulation of the small intestine. After the secretory function of the pancreas is excluded, two stages of compensatory--adaptive changes occur in the secretory activity of small intestine: first the compensation is due to less energy--consuming processes (recretion of the blood enzymes), and further the compensatory mechanisms of the small intestine become involved.

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What this paper is about

In chronic experiments on dogs, soon after ligation of the pancreatic duct, amylase increases in the peripheral blood as well as the total amylase and lipase release in liquid and solid portions of the secret from isolated parts of the small intestine. The alpha--amylase release was shown to depend on the level of the blood amylolytic activity and on secretory activity of small intestine. The alpha--amylase and lipase release is more increased at mechanical rather than at chemical stimulation of the small intestine. After the secretory function of the pancreas is excluded, two stages of compensatory--adaptive changes occur in the secretory activity of small intestine: first the compensation is due to less energy--consuming processes (recretion of the blood enzymes), and further the compensatory mechanisms of the small intestine become involved.

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Available abstract

In chronic experiments on dogs, soon after ligation of the pancreatic duct, amylase increases in the peripheral blood as well as the total amylase and lipase release in liquid and solid portions of the secret from isolated parts of the small intestine. The alpha--amylase release was shown to depend on the level of the blood amylolytic activity and on secretory activity of small intestine. The alpha--amylase and lipase release is more increased at mechanical rather than at chemical stimulation of the small intestine. After the secretory function of the pancreas is excluded, two stages of compensatory--adaptive changes occur in the secretory activity of small intestine: first the compensation is due to less energy--consuming processes (recretion of the blood enzymes), and further the compensatory mechanisms of the small intestine become involved.

Key concepts: Small intestine, Lipase, Amylase, Pancreas, Internal medicine, Secretion, Endocrinology, Enzyme

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