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[Neuropsychic effects of cimetidine and ranitidine. Apropos of 1 case].

R Ducluzeau, Thierry Vial, Dominique Pobel, Jacques Descotes

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Abstract

The incidence of neuropsychiatric complications is very low in patients receiving conventional doses of cimetidine or ranitidine. In this case report, the same patient presented with psychiatric symptoms successively following treatment with both histamine H2-receptor antagonists, suggesting the involvement of histamine-mediated CNS modulation.

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What this paper is about

The incidence of neuropsychiatric complications is very low in patients receiving conventional doses of cimetidine or ranitidine. In this case report, the same patient presented with psychiatric symptoms successively following treatment with both histamine H2-receptor antagonists, suggesting the involvement of histamine-mediated CNS modulation.

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OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The incidence of neuropsychiatric complications is very low in patients receiving conventional doses of cimetidine or ranitidine. In this case report, the same patient presented with psychiatric symptoms successively following treatment with both histamine H2-receptor antagonists, suggesting the involvement of histamine-mediated CNS modulation.

Key concepts: Cimetidine, Ranitidine, Histamine, Medicine, Incidence (geometry), Histamine H2 receptor, Anesthesia, Pharmacology

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