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Combined clofazimine- and dapsone-resistant leprosy. A case report.

Kar Hk, Bhatia Vn, S Harikrishnan

Abstract

A preliminary report is presented on the finding in a patient with lepromatous leprosy relapsing after maintaining clinical inactivity and bacterial negativity with dapsone monotherapy for a period of 23 years. Interestingly, Mycobacterium leprae from the fresh skin lesions revealed resistance to both clofazimine and dapsone by standard mouse foot pad testing.

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Key concepts: Clofazimine, Dapsone, Leprosy, Mycobacterium leprae, Medicine, Lepromatous leprosy, Dermatology, Immunology