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Protective effect of Cynomorii Herba extract on $H_2O_2$-induced cytotoxicity

Myung‐Sook Oh, Do-Rim Kim, Woong-Mo Yang, Mun-Seog Chang, Park Soo-Yeon, Soon-Ah Kang, Seong-Kyu Park

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Abstract

The purpose of this study is to examine the protective effect of Cynomorii herba on -induced cytotoxicity in male germ cells. The effects were studied by a modified MTT assay. Hydrogen peroxide significantly induced cytotoxicity in GC-1 spg cells, and co-treatment or pre-treatment of Cynomorii herba extract has reduced the cytotoxicity in a dose dependant manner. These results suggest that Cynomorii herba extract increases the survival rate of GC-1 spg cells through the antioxidant effect against -induced cytotoxicity.

About this research paper

What this paper is about

The purpose of this study is to examine the protective effect of Cynomorii herba on -induced cytotoxicity in male germ cells. The effects were studied by a modified MTT assay. Hydrogen peroxide significantly induced cytotoxicity in GC-1 spg cells, and co-treatment or pre-treatment of Cynomorii herba extract has reduced the cytotoxicity in a dose dependant manner. These results suggest that Cynomorii herba extract increases the survival rate of GC-1 spg cells through the antioxidant effect against -induced cytotoxicity.

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Available abstract

The purpose of this study is to examine the protective effect of Cynomorii herba on -induced cytotoxicity in male germ cells. The effects were studied by a modified MTT assay. Hydrogen peroxide significantly induced cytotoxicity in GC-1 spg cells, and co-treatment or pre-treatment of Cynomorii herba extract has reduced the cytotoxicity in a dose dependant manner. These results suggest that Cynomorii herba extract increases the survival rate of GC-1 spg cells through the antioxidant effect against -induced cytotoxicity.

Key concepts: Cytotoxicity, MTT assay, Chemistry, Antioxidant, Hydrogen peroxide, Pharmacology, Traditional medicine, In vitro

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