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Are Topical Estrogens Effective for Skin Aging

Craig A. Elmets

Abstract

Aging of the skin is caused by a combination of genetic factors (natural aging) and excessive sun exposure (photoaging). Natural aging appears as fine wrinkles, skin laxity, and sagging; photoaging produces coarse wrinkles. Both processes result, at least in part, from declines in types I and III collagen in the dermis. Topical medications that could restore the youthful appearance of skin are of great …

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Key concepts: Photoaging, Skin Aging, Dermis, Medicine, Dermatology, Sun exposure, Wrinkle, Cosmetic Techniques