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2014•Journal of Changchun University of Traditional Chinese MedicineRequires access

Progress of drug therapy for gout and hyperuricemia

Nie Yin

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Abstract

Currently,primary gout still cannot be cured,for which the blood uric acid is controlled to be less than 360μmol/L mainly by drug therapy while for patients with gouty tophus the blood uric acid is controlled to be less than238 μmol /L. So far,frequently-used drugs are mainly colchicines that treating acute gout by acting on neutrophile granulocyte,selective and non-selective cyclooxygenase inhibitor-nonsteroidal anti-inflammatory drugs( NAIDS),glucocorticoids and xanthine oxidase( XO) inhibitor-allopurinol,etc.

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What this paper is about

Currently,primary gout still cannot be cured,for which the blood uric acid is controlled to be less than 360μmol/L mainly by drug therapy while for patients with gouty tophus the blood uric acid is controlled to be less than238 μmol /L. So far,frequently-used drugs are mainly colchicines that treating acute gout by acting on neutrophile granulocyte,selective and non-selective cyclooxygenase inhibitor-nonsteroidal anti-inflammatory drugs( NAIDS),glucocorticoids and xanthine oxidase( XO) inhibitor-allopurinol,etc.

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Available abstract

Currently,primary gout still cannot be cured,for which the blood uric acid is controlled to be less than 360μmol/L mainly by drug therapy while for patients with gouty tophus the blood uric acid is controlled to be less than238 μmol /L. So far,frequently-used drugs are mainly colchicines that treating acute gout by acting on neutrophile granulocyte,selective and non-selective cyclooxygenase inhibitor-nonsteroidal anti-inflammatory drugs( NAIDS),glucocorticoids and xanthine oxidase( XO) inhibitor-allopurinol,etc.

Key concepts: Medicine, Gout, Allopurinol, Hyperuricemia, Febuxostat, Uric acid, Xanthine oxidase inhibitor, Tophus

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