Comparison of Linezolid vs.Vancomycin in the Treatment of Retention Catheterization Infection Induced by MRSA

OBJECTIVE: To analyze the effectiveness of linezolid vs.vancomycin in the treatment of retention catheterization infection induced by methicillin-resistant staphylococcus aureus(MRSA) infections.METHODS: 53 patients with MRSA infection treated divided into linezolid group(27 cases) and vancomycin group(26 cases).Linezolid group was given linezolid 600 mg every 12 hours,and vancomycin group was given vancomycin 1 g every 12 hours.After 14 days treatment,microbiologic eradications of 2 groups of drugs were analyzed.RESULTS: After 14 days treatment,the cure rates of linezolid group and vancomycin group were 66.7% and 23.1%.There was statistical significance(P0.05).CONCLUSION: The effectiveness of linezolid are similar to those of vancomycin in the treatment of gram-positive bacterial infection,but the cure rate of linezolid is higher than vancomycin in 14 days.