ScholarLens Back to search
2007•Zhongguo xiong-xin xueguan waike linchuang zazhiRequires access

Progress of Human Leukocyte Antigen Typing and Panel Reactive Antibody Testing in Heart Transplantation

Wang Chun-shen

Open publisher page 0 citations

Abstract

Human leukocyte antigen(HLA) is the key antigen mediating rejection and panel reactive antibody(PRA) represent anti-HLA antibodies in circulation.HLA typing and PRA testing are carried out generally before organ transplantation.With research on the relationship among HLA,PRA and heart transplantation developing,the value of HLA typing and PRA testing in heart transplantation has received more attention and their clinical using strategy has been improved.This article will review the strategy of HLA typing,the clinical value of HLA typing,time-selection in HLA typing,reason and mechanism of rising PRA,clinical sense of PRA testing and treatment of sensitized patients.

About this research paper

What this paper is about

Human leukocyte antigen(HLA) is the key antigen mediating rejection and panel reactive antibody(PRA) represent anti-HLA antibodies in circulation.HLA typing and PRA testing are carried out generally before organ transplantation.With research on the relationship among HLA,PRA and heart transplantation developing,the value of HLA typing and PRA testing in heart transplantation has received more attention and their clinical using strategy has been improved.This article will review the strategy of HLA typing,the clinical value of HLA typing,time-selection in HLA typing,reason and mechanism of rising PRA,clinical sense of PRA testing and treatment of sensitized patients.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Human leukocyte antigen(HLA) is the key antigen mediating rejection and panel reactive antibody(PRA) represent anti-HLA antibodies in circulation.HLA typing and PRA testing are carried out generally before organ transplantation.With research on the relationship among HLA,PRA and heart transplantation developing,the value of HLA typing and PRA testing in heart transplantation has received more attention and their clinical using strategy has been improved.This article will review the strategy of HLA typing,the clinical value of HLA typing,time-selection in HLA typing,reason and mechanism of rising PRA,clinical sense of PRA testing and treatment of sensitized patients.

Key concepts: Panel reactive antibody, Typing, Human leukocyte antigen, Medicine, Tissue typing, Heart transplantation, Immunology, Transplantation

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Progress of Human Leukocyte Antigen Typing and Panel Reactive Antibody Testing in Heart Transplantation — Research Paper | ScholarLens