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Hypoxia inducible factor-1α:a key regulator for tumor biological characteristics

QV De

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Abstract

Hypoxia inducible factor-1 α(HIF-1α),is overexpressed in many human tumors.A vast array of genes involved in tumor biological characteristics is regulated by HIF-1α,which weighs heavily in favor of tumor genesis and progression.So far,studies on HIF-1α have became an attracting area of tumor research,which makes scientists better understanding how HIF-1α functions in tumor biological characteristics and provides scientific basis for tumor therapies targeting HIF-1α.

About this research paper

What this paper is about

Hypoxia inducible factor-1 α(HIF-1α),is overexpressed in many human tumors.A vast array of genes involved in tumor biological characteristics is regulated by HIF-1α,which weighs heavily in favor of tumor genesis and progression.So far,studies on HIF-1α have became an attracting area of tumor research,which makes scientists better understanding how HIF-1α functions in tumor biological characteristics and provides scientific basis for tumor therapies targeting HIF-1α.

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Available abstract

Hypoxia inducible factor-1 α(HIF-1α),is overexpressed in many human tumors.A vast array of genes involved in tumor biological characteristics is regulated by HIF-1α,which weighs heavily in favor of tumor genesis and progression.So far,studies on HIF-1α have became an attracting area of tumor research,which makes scientists better understanding how HIF-1α functions in tumor biological characteristics and provides scientific basis for tumor therapies targeting HIF-1α.

Key concepts: Regulator, Hypoxia-inducible factors, Hypoxia (environmental), Cancer research, Tumor hypoxia, Tumor progression, Tumor cells, Master regulator

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