Hepatic Inflammatory Myofibroblastic Tumor: Imaging Findings with Pathologic Correlation
Enhua Xiao
Abstract
Enhua Xiao
Abstract
Purpose To evaluate the imaging findings with clinical features and pathological basis of hepatic inflammatory myofibroblastic tumor (HIMT). Materials and Methods Twenty-one patients with pathology proven HIMT were reviewed retrospectively. Twenty-one patients underwent CT, and three underwent additional MRI. Results All tumors in 21 patients were in right hepatic lobe. The mean diameter was (4.1±1.2) cm. The lesions were low density on non contrast CT. MRI was manifested as hypointense lesions on unenhanced T1WI and isointensity or mild hyperintensity on unenhanced T2WI. Enhancement manifestations in dynamic contrast scan showed 8 cases of entire tumor enhancement, 6 ring-shaped enhancement; 4 septal enhancement; 3 no enhancement. Pathological examination showed different degrees of organized necrosis, fibrous tissue and inflammatory cells infiltration. Conclusion The CT and MR features of HIMT are characteristic, which correlate with its pathological findings.
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Purpose To evaluate the imaging findings with clinical features and pathological basis of hepatic inflammatory myofibroblastic tumor (HIMT). Materials and Methods Twenty-one patients with pathology proven HIMT were reviewed retrospectively. Twenty-one patients underwent CT, and three underwent additional MRI. Results All tumors in 21 patients were in right hepatic lobe. The mean diameter was (4.1±1.2) cm. The lesions were low density on non contrast CT. MRI was manifested as hypointense lesions on unenhanced T1WI and isointensity or mild hyperintensity on unenhanced T2WI. Enhancement manifestations in dynamic contrast scan showed 8 cases of entire tumor enhancement, 6 ring-shaped enhancement; 4 septal enhancement; 3 no enhancement. Pathological examination showed different degrees of organized necrosis, fibrous tissue and inflammatory cells infiltration. Conclusion The CT and MR features of HIMT are characteristic, which correlate with its pathological findings.
Key concepts: Medicine, Pathological, Contrast enhancement, Hyperintensity, Radiology, Pathology, Magnetic resonance imaging, Infiltration (HVAC)