The Analysis of Atypical Chronic Myelogenous Leukemia

Objective: To investigate the diagnosis of atypical chronic myelogenous leukemia.Methods: Through the comparison between atypical chronic myelogenous leukemia (12 cases) and typical chronic myelogenous leukemia (23 cases), we can find out that atypical chronic myelogenous leukemia was different from typical chronic myelogenous leukemia in clinical characteristics and morphology features.Results:First of all,the patients' age is always old.In most cases, there was not anemia but platelet was slightly higher than the normal, swelling of spleen was not unconspicuous, and the neutrophil alkaline phosphatase score was normal or slightly decreased.Philadelphia (Ph) chromosome was undetectable by polymerase chain reaction (PCR) as well.Conclusion: To diagnose this disease, the course of disease must be observed in succession which is aggravated along with the time passing and the other therapies are invalid.