The clinical value of multi-slice CT angiography in evaluation of intracranial artery stenosis and occlusive disease

Objective To evaluate the clinical value of multi-slice CT angiography (CTA) in diagnosis of intracranial artery stenosis and occlusion compared with DSA measure. Methods A total of 32 patients with ischemic cerebrovascular lesions were enrolled,male 23,female 9,aged 48 ~ 75 years,mean age 57 years. All patients were performed CTA and DSA (digital subtal angiography) . Two studies were performed within a 15 day period. Two radiologists reviewed the CTA and DSA images independently. The steonsis rates were calculated and graded, and the narrowest portion of stenosis lumen diameter was measured. Results The DSA data was defined as the reference standard. And 74 abnormal artery segments were found by CTA, the lesion numbers and location of the stenosis were coincided with DSA results. The sensitivity,specificity and accuracy of CTA in diagnosis the moderate stenosis were 94.3 %,98.8 % and 98.6 % respectively;severe stenosis were 73.7 %,99.7 % and 99.7 %;occlusion were 91.7 %,99.8 % and 100 %,respectively. The difference between CTA and DSA in evaluation stenosis rates and steonsis lumen diameter had no statistical significance. Conclusion The CTA is a reliable approach in evaluating the intracranial stenosis and occlusion. The specificity and accuracy of CTA results are similar to that of DSA in most cases.