The efficacy of low molecular weight heparin to prevent postoperative deep vein thrombosis of elderly hip fracture patients

Objective:To observe the efficacy and safety of the low molecular weight heparin (low molecular weight heparins calcium injection, LMWH) to prevent postoperative deep vein thrombosis (deep venous thrombosis, DVT) in elderly hip fracture patients.Method:Fifty patients undergoing surgery were randomly divided into two groups. A group use low molecular weight heparin, and B group use common vasoactive drugs. The incidence of deep vein thrombosis were detected by lower limb ultrasonography after 14~20 days of operation. Result: There were no cases of patients with deep venous thrombosis in group A, and there were 6 cases of deep venous thrombosis occurred in group B(24%). The difference between the two groups was significant (P0.05). Both the two groups have no obvious bleeding. The blood loss in group A was 295±80 ml and 272±80 ml in B group. There were no significant difference between the two groups (P0.05). Conclusion:The perioperative application of low molecular weight heparin can be safe and effective in prevention of the lower extremity deep vein thrombosis in elderly hip fracture patients.