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Relations Between Insulin Resistance and Metabolic Disorders in Middle- aged People

WU Aizh

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Abstract

Objective To explore the relations between insulin resistance and metabolic disorders in middle - aged people. Methods 180 subjects aged 65.3 ± 9.2 years were divided into four groups: control group, insulin resistance syndrome group, hyper-lipemia group and NIDDM group. Plasma glucose was measured by the enzyme method. Serum insulin was measured by the radioim-munoassay,The estimate of insulin resistance by HOMA was calculated with formula fasting serum insulin(mIU/L)× fasting plasma glucose (mmol/L)/22.5. Results Statistical analysis showed that HOMA - IR in three metabolic disorder groups were obvious higher than that in control group. Conclusion Prevalence of Insulin resistance is existed in middle - aged people with metabolic disorders.

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What this paper is about

Objective To explore the relations between insulin resistance and metabolic disorders in middle - aged people. Methods 180 subjects aged 65.3 ± 9.2 years were divided into four groups: control group, insulin resistance syndrome group, hyper-lipemia group and NIDDM group. Plasma glucose was measured by the enzyme method. Serum insulin was measured by the radioim-munoassay,The estimate of insulin resistance by HOMA was calculated with formula fasting serum insulin(mIU/L)× fasting plasma glucose (mmol/L)/22.5. Results Statistical analysis showed that HOMA - IR in three metabolic disorder groups were obvious higher than that in control group. Conclusion Prevalence of Insulin resistance is existed in middle - aged people with metabolic disorders.

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Available abstract

Objective To explore the relations between insulin resistance and metabolic disorders in middle - aged people. Methods 180 subjects aged 65.3 ± 9.2 years were divided into four groups: control group, insulin resistance syndrome group, hyper-lipemia group and NIDDM group. Plasma glucose was measured by the enzyme method. Serum insulin was measured by the radioim-munoassay,The estimate of insulin resistance by HOMA was calculated with formula fasting serum insulin(mIU/L)× fasting plasma glucose (mmol/L)/22.5. Results Statistical analysis showed that HOMA - IR in three metabolic disorder groups were obvious higher than that in control group. Conclusion Prevalence of Insulin resistance is existed in middle - aged people with metabolic disorders.

Key concepts: Insulin resistance, Medicine, Internal medicine, Metabolic syndrome, Insulin, Endocrinology, Metabolic disorder, Plasma glucose

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