Effect Observation of VSD Combined with Split-thickness Skin Graft in the Treatment of Skin Defects with Infection

Objective To investigate the effect of vacuum sealing drainage(VSD) combined with split-thickness skin graft for the treatment of infectious skin defect. Methods A retrospective analysis was conducted on 60 cases(experimental group) with skin defect and infection admitted in our department from 2012 to 2014. The experimental group were given debridement and VSD coverage, sensitive drugs based on the germiculture and VSD combined with split-thickness skin graft when the result of bacterial culture was negative and a lot of granulation tissues grew on the wound. The other 60 cases with skin defect and infection admitted during the same period were selected as the control group and given the traditional free skin grafting. The curative effect was compared between the two groups. Results The incidence of fever was 5.0% and postoperative sinus formation rate was 10.0% in the experimental group, and that was 16.7%, 20.0%, respectively in the control group, the differences between the two groups were statistically significant(P0.05). Conclusion Vacuum sealing drainage has high value of clinical application, which is worthy of promotion.