2010•Journal of Shanxi Medical College for Continuing EducationRequires access
Drug-Resistance Characteristics of Escherichia Coli and Gene Analysis on AmpC Enzymes
Jianrong Rong
Open publisher page 0 citations
Abstract
Objective: To investigate the drug-resistance phenotype of Escherichia coli which produces extended-spectrum β-lactamases(ESBLs) and AmpC enzymes genotype.Methods: Escherichia coli producing both ESBLs and AmpC strains were screened and detected by double-disc diffusion and E-test.And the AmpC enzymes drug-resistance genotype was confirmed by PCR gene amplification method.Results: There was 1 AmpC strain among 68 strains producing extended-spectrum β-lactamases(ESBLs) Escherichia coli.Conclusion:Escherichia coli is a common bacterium which produces ESBLs and produces strains of AmpC enzymes at the same time to make the drug-resistance increased.It is important to detect and monitor the Escherichia coli in the laboratory.