2015Research and Practice on Chinese MedicinesRequires access

Optimization of Extracting Process of Bimingan Granule with Multi-indices by Orthogonal Test

Lu Cha

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Abstract

Objective To optimize the extraction process of Biminggan granules. Methods Based on comprehensive score index of the water extraction yield, the content of AstragalosideⅣ and Ephedrine hydrochloride, investigate the influence of amount of adding water, extracting time and extracting times on extraction process by the orthogonal test. Results The best extraction process were as follows: 10 times the amount of water added and extracted 3 times, each time 60 min. Conclusion This optimized extraction process was simple, stable and can provide the basis for the development and utilization of Biminggan granule.

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Objective To optimize the extraction process of Biminggan granules. Methods Based on comprehensive score index of the water extraction yield, the content of AstragalosideⅣ and Ephedrine hydrochloride, investigate the influence of amount of adding water, extracting time and extracting times on extraction process by the orthogonal test. Results The best extraction process were as follows: 10 times the amount of water added and extracted 3 times, each time 60 min. Conclusion This optimized extraction process was simple, stable and can provide the basis for the development and utilization of Biminggan granule.

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Available abstract

Objective To optimize the extraction process of Biminggan granules. Methods Based on comprehensive score index of the water extraction yield, the content of AstragalosideⅣ and Ephedrine hydrochloride, investigate the influence of amount of adding water, extracting time and extracting times on extraction process by the orthogonal test. Results The best extraction process were as follows: 10 times the amount of water added and extracted 3 times, each time 60 min. Conclusion This optimized extraction process was simple, stable and can provide the basis for the development and utilization of Biminggan granule.

Key concepts: Granule (geology), Chromatography, Water extraction, Extraction (chemistry), Process (computing), Process engineering, Mathematics, Computer science

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