2010•Xinjiang Yike Daxue xuebaoRequires access
Clinical characteristic and HBV genotype of HBV carriers in Xinjiang
Liu Hao
Open publisher page 0 citations
Abstract
Objective To understand HBV genotype distributed and clinical characteristic by HBV infection disease.Methods HBV genotype distributed and clinical characteristic by HBV infection disease with HBV genotyping were analyzed by polymerase chain reaction(PCR)-restriction fragment length polymorphism.Results Of the 331 patients investigated in 2007,genotype B,C,C/D,D were accounted 14.8%(49/331),72.8%(241/331),9.7%(32/331) and 2.7%(9/331) respectively.In four HBV genotypes,C genotype had significant differences in age compared with B,C/D genotypes(P0.05).C genotype age had significant differences compared with B,C/D,HBeAg,CH,LC,HCC(P0.05).Sex,ALT,AST,TBIL,ALB had no significant differences in these four types(P0.05).Conclusion The C genotype is main genotype in Xinjiang with chronic HBV infection.C genotype leads to patient′s condition severity.