Anesthesia with Propofol combined with remifentanil in artificial abortion

Objective To investigate the anesthesia effect of Propofol combined with remifentanil in artificial abortion and the possible impact on respiratory system and circulation system.Method Forty patients undergoing artificial abortion(ASA I～II,age: 18～32 years,weight: 43～62kg) were allocated into two groups randomly as Propofol combined with remifentanil group(group R) and Propofol group(group P),with 20 patients in each group.Group R was administered Propofol(2mg/kg,i.v.) combined with remifentanil(0.75μg/㎏,i.v.) and group P was administered Propofol(3mg/kg,i.v.).The two groups received the same operation with the same method,and there was no significant meaning of age,weight and abortion time between the two groups(P0.05).Blood pressure(BP),heart rate(HR),saturation of blood oxygen(SpO2),awake time and anesthesia effect were observed pre-anesthesia,post-anesthesia and end of anesthesia,respectively.Results Induction time and awake time of group R were significantly shorter than that of group P(P0.05);The decrease of BP,HR and SpO2 in group P 2min after anesthesia were more obvious than that of group R(P0.05).The anesthesia effect in group R was better than that of group P(P0.05).Conclusion Anesthesia with Propofol plus remifentanil in artificial abortion has a definite effect of analgesia.Little dosage,working and waking fast,little inhibition in respiritory and circulation system make it better than anesthesia with Propofol alone.